All the seminars, past and upcoming
Start Monday April 3rd at 4pm (CET, Berlin/Paris)
(3 pm London/Lisbon, 10am New-York, 7am San Francisco, 5pm Tel Aviv - check the YouTube stream to be sure of the time zone)
Link to the Zoom conference: https://univ-grenoble-alpes-fr.zoom.us/j/96536900963?pwd=Q3Q5dlRONDhDUjh3NGwrYjhDYXlNdz09 (updated)
Link to the YouTube stream: https://youtu.be/VYIKBJq_coM
Main Speaker: Cynthia Sharma, Professor, Institute of Molecular Infection Biology (IMIB), University of Würzburg, Germany (Link)
Regulatory RNAs in pathogenic Epsilonproteobacteria
Non-coding RNAs and RNA-protein (RNP) complexes play central roles in diverse physiological processes in all kingdoms of life. Research in our lab focuses on RNA-based processes in the two pathogenic Epsilonproteobacteria Helicobacter pylori, the cuasative agent of gastric cancer, and the related food-borne pathogen Campylobacter jejuni. We are especially interested in the roles of small, regulatory RNAs (sRNAs) and RNPs in virulence control as well as novel mechanisms of gene regulation. For example, we have discovered new connections between so-called phase-variation at length variable DNA repeats and post-transcriptional regulation. I will present our work on sRNAs from H. pylori and C. jejuni that target variable G-repeats and regulate genes involved in host colonization as well as antibiotic sensitivity. Moreover, we recently identified a sRNA that is itself regulated by a phase-variable repeat and acts as a central regulator of the major virulence factors of H. pylori.
Short session speaker (8 minutes long): Fabian König
Title: A 3´UTR-derived, processed small RNA modulates flagellar biogenesis by repression of the anti-sigma factor FlgM in
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.